Jane Tomlinson has died of breast cancer after a long battle against the disease, her family has announced.
The mum-of-three, who was diagnosed with terminal cancer seven years ago, has raised more than £1.75m for good causes in a series of gruelling challenges.
Her husband Mike and children Suzanne, Rebecca and Steven said she died at St Gemma's Hospice in Leeds last night.
In a statement, they added: "We are as a family heartbroken at this loss but we know this extends to all her family and friends.
"Jane has always said her family has been the greatest joy in life and we feel honoured to have been blessed with such a wonderful person."
The Prime Minister has paid tribute to the cancer fundraiser.
Gordon Brown said: "The whole country will be greatly saddened by the death of Jane Tomlinson, and our thoughts are with her husband, her three children and all her family and friends.
"Jane's mission in life was a simple one: to make the most of every day and to help others, and she not only achieved that several times over, but inspired millions of others along the way."
When Mrs Tomlinson was told she had breast cancer, doctors gave her just a few months to live.
She has since drawn praise from around the world for feats which have included cycling across the US, taking part in the notorious Florida Ironman event and cycling from Rome to her home in West Yorkshire.
She received a CBE for her work in June this year.
Mrs Tomlinson's husband and children paid tribute to her for her fundraising efforts.
They said: "It is to her remarkable achievement that it became the norm for her to complete one marathon or triathlon after another.
"Everyone became aware of her achievements and we hope as a result so the expectations of what can be achieved by the terminally ill have been raised."
The Tomlinson family asked for time to grieve in private but full funeral details are expected to be made public in the near future
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